![Bextra, a COX-2 inhibitor once used in the treatment of arthritis, contains an isoxazole ring. Why is the ring aromatic? | Homework.Study.com Bextra, a COX-2 inhibitor once used in the treatment of arthritis, contains an isoxazole ring. Why is the ring aromatic? | Homework.Study.com](https://homework.study.com/cimages/multimages/16/66911223976291339131022447.png)
Bextra, a COX-2 inhibitor once used in the treatment of arthritis, contains an isoxazole ring. Why is the ring aromatic? | Homework.Study.com
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IN VITRO METABOLISM STUDIES ON THE ISOXAZOLE RING SCISSION IN THE ANTI-INFLAMMATORY AGENT LEFLUNOMIDE TO ITS ACTIVE α-CYANOENOL METABOLITE A771726: MECHANISTIC SIMILARITIES WITH THE CYTOCHROME P450-CATALYZED DEHYDRATION OF ALDOXIMES | Drug Metabolism
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Reductive isoxazole ring opening of the anticoagulant razaxaban is the major metabolic clearance pathway in rats and dogs. | Scinapse
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Harnessing the Intrinsic Photochemistry of Isoxazoles for the Development of Chemoproteomic Crosslinking Methods | bioRxiv
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Fig. 1. | Reductive Isoxazole Ring Opening of the Anticoagulant Razaxaban Is the Major Metabolic Clearance Pathway in Rats and Dogs | Drug Metabolism & Disposition
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Proposed mechanisms for the metabolic isoxazole ring opening in the... | Download Scientific Diagram
![An Efficient Access to 3,5‐Disubstituted Isoxazoles with Anthranilate Ester Moiety: Alkaloid Lappaconitine – Aryl Conjugates with an Isoxazole Linker - Cheremnykh - 2021 - Asian Journal of Organic Chemistry - Wiley Online Library An Efficient Access to 3,5‐Disubstituted Isoxazoles with Anthranilate Ester Moiety: Alkaloid Lappaconitine – Aryl Conjugates with an Isoxazole Linker - Cheremnykh - 2021 - Asian Journal of Organic Chemistry - Wiley Online Library](https://onlinelibrary.wiley.com/cms/asset/ddc327a7-390c-4539-8cad-866bfba6c0e9/ajoc202100474-toc-0001-m.jpg)
An Efficient Access to 3,5‐Disubstituted Isoxazoles with Anthranilate Ester Moiety: Alkaloid Lappaconitine – Aryl Conjugates with an Isoxazole Linker - Cheremnykh - 2021 - Asian Journal of Organic Chemistry - Wiley Online Library
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PDF] In vitro metabolism studies on the isoxazole ring scission in the anti-inflammatory agent lefluonomide to its active alpha-cyanoenol metabolite A771726: mechanistic similarities with the cytochrome P450-catalyzed dehydration of aldoximes. | Semantic
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A base promoted multigram synthesis of aminoisoxazoles: valuable building blocks for drug discovery and peptidomimetics - RSC Advances (RSC Publishing) DOI:10.1039/C6RA02365G
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Transition Metal‐Mediated Functionalization of Isoxazoles: A Review - Madhavan - 2021 - Asian Journal of Organic Chemistry - Wiley Online Library
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